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Adrian V S Hill Selected Research

Malaria

10/2022Production of a high purity, C-tagged hepatitis B surface antigen fusion protein VLP vaccine for malaria expressed in Pichia pastoris under cGMP conditions.
1/2022Deep Immune Phenotyping and Single-Cell Transcriptomics Allow Identification of Circulating TRM-Like Cells Which Correlate With Liver-Stage Immunity and Vaccine-Induced Protection From Malaria.
4/2021A VLP for validation of the Plasmodium falciparum circumsporozoite protein junctional epitope for vaccine development.
1/2021Safety and Immunogenicity of ChAd63/MVA Pfs25-IMX313 in a Phase I First-in-Human Trial.
1/2021Poor CD4+ T Cell Immunogenicity Limits Humoral Immunity to P. falciparum Transmission-Blocking Candidate Pfs25 in Humans.
1/2021Efficacy of a low-dose candidate malaria vaccine, R21 in adjuvant Matrix-M, with seasonal administration to children in Burkina Faso: a randomised controlled trial.
1/2021Ultra-low dose immunization and multi-component vaccination strategies enhance protection against malaria in mice.
1/2021Screening of viral-vectored P. falciparum pre-erythrocytic candidate vaccine antigens using chimeric rodent parasites.
1/2020Modification of Adenovirus vaccine vector-induced immune responses by expression of a signalling molecule.
1/2020Generation of Novel Plasmodium falciparum NF135 and NF54 Lines Expressing Fluorescent Reporter Proteins Under the Control of Strong and Constitutive Promoters.
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Adrian V S Hill Research Topics

Disease

150Malaria
10/2022 - 01/2002
66Infections
10/2021 - 04/2003
38Tuberculosis (Tuberculoses)
01/2020 - 03/2002
18Vaccinia
03/2021 - 10/2007
18Communicable Diseases (Infectious Diseases)
03/2020 - 07/2007
13Human Influenza (Influenza)
01/2022 - 01/2011
12Falciparum Malaria (Plasmodium falciparum Malaria)
01/2021 - 01/2005
9Bites and Stings (Sting)
01/2019 - 02/2005
8Parasitemia
01/2020 - 06/2003
7COVID-19
12/2021 - 01/2020
7Fowlpox
12/2009 - 06/2004
6Neoplasms (Cancer)
01/2018 - 12/2005
6Acquired Immunodeficiency Syndrome (AIDS)
03/2012 - 05/2002
5HIV Infections (HIV Infection)
01/2021 - 04/2006
5Inflammation (Inflammations)
01/2020 - 12/2003
5Sepsis (Septicemia)
03/2017 - 03/2011
5Pneumococcal Infections
01/2015 - 05/2002
4Pain (Aches)
12/2021 - 01/2011
4Fever (Fevers)
10/2021 - 11/2007
4Prostatic Neoplasms (Prostate Cancer)
01/2020 - 01/2016
4Rift Valley Fever
01/2019 - 12/2013
4Hepatitis B
06/2015 - 01/2005
3Anemia
01/2019 - 01/2013
3Bacteremia
01/2019 - 06/2016
3Persistent Infection
08/2016 - 09/2003
2Headache (Headaches)
12/2021 - 01/2020
2Ageusia (Hypogeusia)
10/2021 - 01/2021
2Dyspnea (Shortness of Breath)
10/2021 - 01/2021
2Cough
10/2021 - 01/2021
2Anosmia
10/2021 - 01/2021
2Rheumatic Heart Disease (Rheumatic Heart Diseases)
01/2020 - 11/2017
2Ebola Hemorrhagic Fever
01/2019 - 01/2018
2Rabies (Hydrophobia)
10/2018 - 12/2009
2Parasitic Diseases (Parasitic Disease)
09/2016 - 10/2011
2Chronic Hepatitis C
08/2016 - 05/2016
2Vesicular Stomatitis
04/2016 - 03/2007

Drug/Important Bio-Agent (IBA)

165VaccinesIBA
10/2022 - 01/2002
77AntigensIBA
01/2022 - 03/2002
50Proteins (Proteins, Gene)FDA Link
10/2022 - 04/2003
31Malaria VaccinesIBA
01/2021 - 01/2002
20EpitopesIBA
01/2018 - 03/2002
15ThrombospondinsIBA
01/2018 - 04/2003
15MVA 85AIBA
01/2013 - 07/2004
14AntibodiesIBA
01/2022 - 08/2008
131- acetyl- 1,2,3,3a,8,8a- hexahydro- 8a- hydroxy- 5- methoxypyrrolo(2,3- b)indole (CHMI)IBA
12/2019 - 06/2012
11Peptides (Polypeptides)IBA
04/2021 - 03/2004
11DNA (Deoxyribonucleic Acid)IBA
02/2011 - 06/2003
10CytokinesIBA
03/2017 - 12/2004
9Subunit VaccinesIBA
12/2015 - 01/2004
9Merozoite Surface Protein 1 (MSA1)IBA
04/2014 - 03/2002
6ChAdOx1 nCoV-19IBA
12/2021 - 01/2020
6Pharmaceutical PreparationsIBA
01/2020 - 08/2006
6Antimalarials (Antimalarial Agents)IBA
01/2016 - 03/2007
5Nucleic AcidsIBA
10/2021 - 01/2014
5Interferon-gamma (Interferon, gamma)IBA
06/2012 - 04/2003
5Tuberculosis VaccinesIBA
06/2011 - 05/2006
4Neutralizing AntibodiesIBA
04/2021 - 12/2011
4IronIBA
01/2020 - 01/2013
4Biomarkers (Surrogate Marker)IBA
01/2020 - 01/2013
4T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA
07/2010 - 03/2004
3EnzymesIBA
01/2020 - 11/2005
3HLA Antigens (Human Leukocyte Antigens)IBA
01/2020 - 02/2005
3Transcription Factors (Transcription Factor)IBA
01/2019 - 07/2007
3Rabies Vaccines (Rabies Vaccine)FDA Link
10/2018 - 05/2015
3Glycoproteins (Glycoprotein)IBA
07/2017 - 01/2016
3Antiviral Agents (Antivirals)IBA
08/2016 - 07/2012
3InterferonsIBA
05/2015 - 06/2003
3Influenza Vaccines (Influenza Vaccine)FDA Link
01/2014 - 06/2012
3LigandsIBA
02/2013 - 12/2003
3Viral VaccinesIBA
03/2011 - 12/2007
3HLA-DRB1 Chains (HLA DRB1)IBA
07/2010 - 06/2005
3Synthetic Vaccines (Recombinant Vaccines)IBA
04/2009 - 02/2005
2Hepatitis B Surface Antigens (HBsAg)FDA Link
10/2022 - 07/2005
2MenACWYIBA
10/2021 - 01/2020
2Matrix-MIBA
01/2021 - 01/2018
2Transferrin (beta 2 Transferrin)IBA
01/2020 - 01/2019
2Cancer VaccinesIBA
01/2020 - 01/2016
2Luminescent ProteinsIBA
01/2020 - 01/2019
2Ebola VaccinesIBA
01/2020 - 01/2019
2Ferritins (Ferritin)IBA
01/2020 - 01/2019
2Hemoglobins (Hemoglobin)IBA
01/2019 - 01/2013
2HepcidinsIBA
01/2019 - 01/2019
2Messenger RNA (mRNA)IBA
01/2019 - 09/2010
2Immune Checkpoint InhibitorsIBA
01/2018 - 07/2017
2artemisinin (artemisinine)IBA
01/2018 - 12/2015
2Immunoglobulin G (IgG)IBA
01/2017 - 12/2011
2Long Noncoding RNAIBA
06/2016 - 02/2013
2Adenovirus VaccinesIBA
02/2016 - 01/2013
2Mannose-Binding Lectin (Mannan-Binding Lectin)IBA
09/2015 - 01/2010
2Interleukin-4 (Interleukin 4)IBA
05/2015 - 05/2007
2Interleukin-2 (IL2)IBA
05/2015 - 11/2006
2VirosomesIBA
05/2015 - 12/2009
2N-acetyltalosaminuronic acid (NAT)IBA
01/2015 - 01/2014
2Recombinant ProteinsIBA
12/2014 - 01/2012

Therapy/Procedure

7Therapeutics
01/2018 - 07/2010
5Immunotherapy
01/2020 - 01/2016
2Intramuscular Injections
01/2020 - 01/2014
2Critical Care (Surgical Intensive Care)
01/2017 - 01/2016
2Precision Medicine
01/2017 - 01/2016
2Insecticide-Treated Bednets
12/2015 - 01/2004